Last updated: August 20, 2026
Every claim made on this site about a Sheni Labs ingredient is backed by a verifiable source, linked below. We cite nutrient function and established safety data — not disease-outcome studies, since a supplement is not a treatment, and citing disease research in this context would misrepresent what the evidence actually shows.
Vitamin D3
1. Tolerable intake and safety.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the Tolerable Upper Intake Level of vitamin D. EFSA Journal 2012;10(7):2813.
Supports: safe dosing range referenced on the Science and Vitamin D3 Facts pages.
2. Nutrient Reference Value.
The EU NRV system explained — GMJ News. Primary legislation: Regulation (EU) No 1169/2011, Annex XIII.
Supports: the 1,000% NRV figure on the Vitamin D3 product page (50 µg against the 5 µg EU reference value).
3. How vitamin D becomes active in the body.
“How Vitamin D Becomes Active: The Three-Organ Pathway Explained” — GMJ News
Supports: the mechanism described on the Science page.
4. Why D3, not D2.
“Vitamin D2 Supplements May Lower Body’s More Effective D3 Levels, Study Warns” — GMJ News
Supports: the D3-over-D2 absorption comparison on the Science and Vitamin D3 Facts pages.
Related product: Sheni Labs Vitamin D3 · Details · Buy →
Omega-3 (EPA/DHA)
1. Global omega-3 deficiency prevalence.
Why 3 in 4 People Worldwide Don’t Get Enough Omega-3 — GMJ News
Supports: the 76% global population deficiency figure referenced on the Omega-3 product page.
2. EPA/DHA and cardiovascular health — EFSA health claim.
EFSA Panel on Dietetic Products, Nutrition and Allergies. Scientific Opinion on the substantiation of health claims related to EPA, DHA, DPA and maintenance of normal blood pressure, maintenance of normal concentrations of triglycerides in blood. EFSA Journal 2010;8(10):1796.
Supports: cardiovascular function references on the Science page.
3. Recommended intake for EPA+DHA.
EFSA Panel on Dietetic Products, Nutrition and Allergies. Scientific Opinion on Dietary Reference Values for fats. EFSA Journal 2010;8(3):1461.
Supports: the 250 mg/day minimum recommendation referenced in the product page NRV footnote.
Related product: Sheni Labs Omega-3 · Details · Buy →
Vitamin E
1. Nutrient Reference Value.
Regulation (EU) No 1169/2011 of the European Parliament and of the Council, Annex XIII.
Supports: the EU NRV of 12 mg alpha-tocopherol and the 1,117% NRV figure on the Vitamin E product page.
2. Natural vs synthetic tocopherol bioavailability.
Burton GW, Traber MG, Acuff RV, et al. Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E. Am J Clin Nutr. 1998;67(4):669–684.
Supports: the natural d-alpha-tocopherol preference stated on the Science and product pages.
3. Tolerable upper intake level.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the Tolerable Upper Intake Level of vitamin E. EFSA Journal 2015;13(7):4149.
Supports: safety context for the 134 mg dose on the Vitamin E product page.
Related product: Sheni Labs Vitamin E · Details · Buy →
Astaxanthin
1. Skin elasticity — randomised controlled trial.
Tominaga K, Hongo N, Fujishita M, Takahashi Y, Adachi Y. Protective effects of astaxanthin on skin deterioration. J Clin Biochem Nutr. 2017;61(1):33–39.
Supports: the skin elasticity and hydration claims on the Science and Astaxanthin product pages.
2. UV-related oxidative stress — clinical evidence.
Astaxanthin and Skin Health: What Clinical Trials Actually Show — GMJ News
Supports: UV oxidative stress marker reductions referenced on the Science page.
3. Mitochondrial effects and longevity — model organism research.
Astaxanthin and Mitochondria: What Aging Research Actually Shows — GMJ News
Supports: the mitochondrial/lifespan references on the Astaxanthin product page. Note: this work is in model organisms; human longevity benefit is not established.
Related product: Sheni Labs Astaxanthin · Details · Buy →
CoQ10 (Ubiquinol)
1. Age-related CoQ10 decline.
CoQ10 Declines With Age: The Cellular Energy Story — GMJ News
Supports: the ~40% decline by age 40 referenced on the Science and CoQ10 product pages.
2. Ubiquinol vs ubiquinone bioavailability.
Ubiquinol vs Ubiquinone: The CoQ10 Bioavailability Difference, Explained Simply — GMJ News
Supports: the choice of ubiquinol over ubiquinone stated on the Science page.
3. Warfarin interaction.
Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and ginkgo biloba on warfarin dosage in stable, long-term warfarin-treated outpatients. Thromb Haemost. 2002;87(6):1075–1076.
Supports: the anticoagulant interaction warning on the CoQ10 product page.
Where evidence is early-stage or mixed, we say so directly rather than presenting it as settled. This list grows as the product line grows — every new ingredient gets the same citation treatment before any claim about it is published.
Related product: Sheni Labs CoQ10 · Details · Buy →
Vitamin K2 (MK-7)
1. K2 vs K1, and how MK-7 works.
K2 vs K1: Why Menaquinones Reach Bone and Blood Vessels — GMJ News
Supports: the osteocalcin / matrix Gla protein mechanism on the Vitamin K2 product and Science pages.
2. All-trans vs cis isomer quality issue.
All-trans vs Cis MK-7: The Isomer Problem Most Supplement Labels Hide — GMJ News
Supports: the isomer-purity test published on the Vitamin K2 testing page.
3. K2 + D3 pairing.
Vitamin D3 + K2: How the Pairing Works — GMJ News
Supports: the calcium-direction rationale on the Vitamin K2 product page. Note: warfarin interaction warning applies. Vitamin K and Warfarin: What Anticoagulated Patients Must Know — GMJ News.
Related product: Sheni Labs Vitamin K2 · Details · Buy →
Vitamin B12 (Methylcobalamin)
1. Why high-dose oral B12 is the evidence-based dose.
Why High-Dose Oral B12 Is the Evidence-Based Dose — GMJ News
Supports: the 500 µg dose rationale (saturable intrinsic-factor absorption, ~1% passive uptake) on the B12 product and Science pages.
2. Methylcobalamin vs cyanocobalamin.
Methylcobalamin vs Cyanocobalamin: The Form Difference Explained — GMJ News
Supports: the form choice on the B12 product page.
3. Who is at risk of B12 deficiency.
Who Is at Risk of B12 Deficiency — GMJ News
Supports: the older-adults / vegan / metformin / PPI risk-group statements.
Related product: Sheni Labs Vitamin B12 · Details · Buy →
Vitamin A (Retinyl Palmitate)
1. Why exactly 100% NRV — the safety-margin argument.
Why Exactly 100% NRV: Vitamin A’s Narrow Safety Margin Explained — GMJ News
Supports: the UL 3,000 µg / teratogenicity rationale and the two-sided potency specification on the Vitamin A pages.
2. Retinol vs beta-carotene (BCO1 conversion genetics).
Retinol vs Beta-Carotene: BCO1 Genetics — GMJ News
Supports: the preformed-retinol choice on the Vitamin A product and Science pages.
Related product: Sheni Labs Vitamin A · Details · Buy →
Ongoing Research
For current research beyond our own product claims: GMJ News (peer-reviewed medical research) · Supplement.ge (independent ingredient database) · SheniEkimi (consumer health education)
